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Since resting rates are considerably less than this, it becomes evident that parasympathetic stimulation normally slows HR.

The heart rate can vary according to the body's physical needs, including the need to absorb oxygen and excrete carbon dioxide.Nervous influence over the heartrate is centralized within the two paired cardiovascular centres of the medulla oblongata.The cardioaccelerator regions stimulate activity via sympathetic stimulation of the cardioaccelerator nerves, and the cardioinhibitory centers decrease heart activity via parasympathetic stimulation as one component of the vagus nerve.Many texts cite the normal resting adult human heart rate as ranging from 60–100 bpm.Bradycardia is a slow heart rate, defined as below 60 bpm at rest.

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